@bdabbff7 @be314b31

No you misunderstood what I said.  First, per the WHO, our best estimate is that LC happens 1 in 10 infections

First off, yes the average across all infections might be 1 in 10, that does not mean your first infection is 1 in 10 as is your second infection. It means when you average it all out it will be 1 in 10. Most studies are looking at the overall average and not differentiating if its your first or second infection.  The evidence we have is that reinfection increases, not decreases, your chance of long covid, just as covid increases risk across the board for a number of other diagnoses like heart disease and diabetes

Yes this is true, nor contrary to what I said.

If you have been infected twice you are, obviously, at a higher risk for having a long term complication than being infected once. That doesnt contradict the idea that on your second infection your risk of long term harm is less than on your first.

I’ll give an arbitrary example that is easy to understand. If on your first infection of covid you have a 1 in 5 chance of long term complications, then on your second infection you have a 1 in 15 chance. Then a person who has been infected twice still has an overall chance of long term complications of about 1 in 4 (so higher than someone infected once). Carry this out to multiple infections and while each infection does increase the risk the risk from any one individual infection is less.

Of course any of this is mostly speculation considering we dont have enough data yet to really make long term conclusions.  If your glasses fog, you haven’t found a mask that fits properly - if it’s sealing correctly, it shouldn’t fog your glasses nor should it be uncomfortable to breathe.

Any mask that seals enough not to fog my glasses is still extremely uncomfortable for many other reasons. I am not wearing hazmat equipment for the rest of my life, full stop. 

 My current model of PASC is that the spike protein creates zombie monocytes: https://www.biorxiv.org/content/10.1101/2021.06.25.449905v1.full

Persistent elevated monocytes on a standard blood assay with no other explanation (any kind of infection) are a possible indication.

Also, while the original article has been taken down, smokers are at higher risk of acute CV symptoms (unsurprising), but significantly lower risk of PASC - and nicotine seems to promote apoptosis of the zombie monocytes.  (But what dose is required?) 

 @bdabbff7 

> You say "even if a study showed clearly".  In addition to casting doubt, this indicates both that you are unacquainted with how research accumulates into knowledge and that you have not, in fact, looked for such a study.

I am a COVID-19 research scientist who has been working on the disease for over 2 years now. Lets not go there with the personal attacks, it makes you look unprofessional and ignorant.

While there are lots of studies that show long-covid and talk about the odds, any honest scientist will tell you COVID is new and our data still very limited. No studies on long-term permanent effects are conclusive this early on in a disease.

> As a research scientist, I assume you are capable of doing a literature survey.  If you take the time to look for papers on sequelae prevalence in reinfection, you will find ample evidence supporting my statements.

Have and do, and yes there are studies that both support and reject many of your assumptions. As is to be expected with such a new disease where the data is still emerging. You can find studies to support almost any invalid assumption you want, the key is understanding the entire body of knowledge and weighing it accordingly.

The funny thing is with my 7 confirmed COVID cases if 1 in 5 was every single infection the chance of me not being permanently disabled would be statistically impossible. Yet here I am perfectly fine... That alone proves the 1 in 5 chance is not compounded across each infection naively.

@be314b31