brave's AI generated this:
Amyloid plaques are a characteristic feature of Alzheimer’s disease, but recent research suggests a more nuanced understanding of their role. A decline in soluble amyloid-beta levels may be the primary driver of the disease, with plaques being a consequence. Toxic amyloid oligomers and inside-cellular origins of plaque formation are also being explored as alternative mechanisms. Ongoing research aims to clarify the complex relationships between amyloid, tau, and other factors to develop effective treatments for Alzheimer’s disease.
essentially, there is a really good reason to think that this amylose formation that is characteristic of alzheimers may be a result of chronic elevated blood glucose, as a secondary mechanism to reduce blood sugar - by stringing it together into amylose
this stuff builds up and sticks to nerves because it is quite nonpolar (like fats and oils) and this interferes with the transmission of nerve signals by constricting the pathway between synapses, by repelling hydroxyl ions (acids) part of the normal salty solution around cells
this is almost certainly related to the optic and muscular problems i have had in the last few years, and part of it has to do with dehydration and part of it with the kidney not working well there is an excessive elimination of potassium
my aunty, who is the child of said oma whose ancestry likely traces back to a dude who looks along similar lines to the dude in thet photo, either 2 or 3 generations back, is not of stock that is used to consuming starches, they are from mountain land and their diet is fruits and meats, and they are known to have been cannibals at some point and very warlike, so it can be safely guessed that they mostly eat meat and starve in between their hunts
the asian genetics associated with tolerating grains and especially rice originate from the mainland of china, and many of the islands and peninsulas that come from this region are full of people who don't have these genetics, and it wiped them out, mostly, the Ainu of japan, the papuans, the aboriginals, they all were devastated by the introduction of starch based diets
she also reported that she found much assistance from supplementing with Boron, and i probably should try to get a hold of her again sometime soon and ask her if she's had any experience with potassium, and foods rich in it like potato and banana (the aunty)
i had a quite dramatic change in my metabolism by adding boron to it and boron and potassium seem to be the two things that help me get back to a decent state of health
and both of these elements are primarily found in leafy and root vegetables, which fits with what you would expect from the diet of austro/indonesian people, whose main diet literally was root starchy veg and green leaves and meat
Okay, I need to look into boron then. I've heard about before but assumed it was one of those whacky health fads. I didn't know about kidneys expelling potassium - why would they do that? I also have reduced kidney function, and I'm sure it plays some role in my high blood pressure
yeah, if you are deficient in boron, your kidneys eliminate calcium and magnesium and this leads to bone and nerve problems
it definitely also affected my mother too, she almost had a hip fracture from a fall down stairs about 15 years ago, and was diagnosed with osteoporosis, which is a calcium deficiency based problem but magnesium is also critical to absorbing calcium so boron is a limiter there, and she also has celiac like me, but not quite as severe
anyhow, yeah, boron is a thing, and i like to joke about how it's the "fifth element" yes, it's element 5.
i will just add that potassium also can be important in this picture, because it clearly is for me, supplementing it has massively reversed problems i have had with cramps and vision
I think I misspoke earlier when I said potassium and sodium have a balance - I'm remembering a thing a little better now and I think it was potassium and calcium that have the balance.
I can attest to the benefits of magnesium - I've felt much better since I started supplementing it. I'm currently doing a vitamin D3/k2, magnesium, and zinc, and its helping a lot.
yeah, that makes sense, i think magnesium limits calcium absorption though, but i never heard this idea that potassium limits/relates to calcium, but it totally makes sense
i always had this impression, sodium and calcium relate to muscle tensing, and magnesium and potassium relate to relaxing, they call it polarising and depolarising, the muscle fibres shorten and lengthen in accordance with ionic/electrostatic effects of current flowing through them, and normally the nerves conduct these opposing voltages with these opposite ions, so it still is consistent with the potassium/magnesium vs calcium/sodium pattern, but it's related to not only the nerves but the muscles as well
muscles function partially by electrostatic effects as well and nerves have this in their function in the dendrites, the "ion channels" that conduct signals, so, yeah, these 4 minerals are definitely all tied together in neuromuscular health
also, just to mention, zinc is related to vitamin C in not just the health of the lungs but also the skin, it is part of the complex of enzymes that synthesise collagen and both organs (skin and lungs) depend on the ability to regenerate the tissue when it is put under stress, which ... anyway, i talked about the fats/vegan diet and how it accelerates the aging of the skin, it also affects the lungs and makes people more vulnerable to cold and flu viruses
zinc helps with this too, and nuts are a key source of zinc
so, yeah, for me this is putting nails in the carnivore diet theory a lot more
i think that humans are primarily adapted to various kinds of diets, we are able to tolerate everything from high starch wheat/rice based diets to carnivore (eskimos and siberians) and root/leaf based diets that you see more in the equatorial regions where these foods are more available
or in other words, humans have adaptations for all three patterns of diet, both grain, meat, and nut/leaf based diets, in various mixtures, but every single individual's health is based on respecting this natural tendency and not imposing some other culture's fucking diet on us
is this some kind of extreme racial purity idea, idk, idc, fuck it this is what my body needs, and it is very clearly basically what would have been available to my great grandfather in the papua highlands lol