@8606bdb4 what happened at Penn is chronic in academia as is funder bias. Regarding this manuscript being rejected by Nature & Science and accepted by Immunology, it’s a reasonable outcome. Modified NA bases by 2005 weren’t novel and their impact on inflammation response to mRNA is more specialized than general interest. Hindsight is 20/20 after all.

External leadership is needed to realize genuine systemic reform. But, if SOS behavior in mCDR is any indication, it’s not happening anytime soon.