Yes, not enough backed evidence IMO and the genetic mutation is a big factor to monitor if you’re predisposed. I do not know of any studies specifically looking at these measures and mechanisms.

Without a health lifestyle, it doesn’t matter either. And until further research and replicated studies, I agree it is a risk to go against what most doctors will tell you without proper supervision and regular scans/testing.

There is a dearth of people, many doctors who even disagree in the paleo/ancestral/carnivore sphere on things such as “do you need fiber”, “fat soluble vitamin toxicity”, “are fruits, honey and dairy ok”, and “impact of environmental toxins”? but most all agree insulin resistance (metabolic disease) and inflammation are the driving causes of CHD and obesity in general.

I don’t believe it’s the best diet for all people; just like I don’t believe people should live in ketosis 24/7. 

 Well thanks for all this info, it was really interesting. Honestly, I'm no expert when it comes to diets, I just try to keep things balanced with animal/plant proteins, fruits/vegetables, fibers but I also enjoy pasta and bread 😄