Hotrightnow and Christpill would probably be two of the most-lively relays, if you could look directly at the feed.
Going to try actively using them, more, so that they have more signal.
You can? In Damus for example, I go to the global magnifying glass tab, click the funnel thing top right, turn off every relay except hotrightright now, back out to home and return to global tab, and bam I see only posts from hotrightnow. Roundabout way, but it works for looking at a “topical relay” feed in Damus.