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 Right now spending bitcoin and one satoshi is no big deal.  I zap and spend all of the time, but what happens way in the future when the value is 1,000 or 10,000 or more times greater.  It could get to the point that requiring a sat is real money and limits the number of people a person can follow.  I admit that is way in the future, but we don't want to design in something that destroys nostr in the future. 
 I see what you mean. Well the solution is quite simple. You just change the price of a follow request over time depending on the market.

At current rate 1 Satoshi is equal to 0 . 00063 which is almost nothing. Not even close to 1 penny.

We're still a long way from Satoshi moving up to the amount you said.

if it goes up 1,000  x price equals $0.63 Bitcoin would be equal to $630,000 for one Bitcoin 

if it goes up 10,000 x price equals  $6.30 Bitcoin would be equal to $630,000,000 for one Bitcoin