well, you can do pretty things to it but the light outline, and the dark on light has to be the same, but you can replace the square pixels with little circles or whatever so long as they are a reasonable size, and due to the optional level of error correction you can wipe out even (any? or at least the centre) 1/9th of the code on higher levels of error correction and put an icon in there
but i don't think this is really needed for a web interface for a management system, this kind of vanity QR is more of a mobile client thing to wow your nocoiner friends with