Many are calling dementia type 3 diabetes. It’s likely a metabolic disease.
Others are saying it's a sleep disorder, a lack of deep sleep preventing the normal brain cleansing mechanisms from removing the byproducts of wakefulness.
I thought John's earlier interview with Patrick Holford was very good. Worth a watch if you are interested in or worried about dementia. Very preventable for most people. https://youtu.be/cXX4iMuwaVQ?si=Qbv3nsKHviXtXs6a