Yes, it is technically possible to build a Layer-2 solution on Ethereum that supports Solana applications. Both Ethereum and Solana are programmable blockchains with robust developer ecosystems, which means that developers have the tools and capabilities to create bridges or interoperability solutions between the two platforms.

One potential approach could involve creating a bridge between Ethereum and Solana that allows tokens and other assets to be transferred between the two chains. This bridge would need to ensure atomicity and security, meaning that transactions are either fully completed on both chains or none at all, to prevent double spending and other issues.

Additionally, developers could explore techniques such as cross-chain communication protocols or interoperability middleware to enable smart contracts and applications deployed on Solana to interact with those on Ethereum. These solutions would need to address challenges related to consensus mechanisms, data formats, and network latency to ensure seamless interoperability between the two chains.

While building a Layer-2 solution supporting Solana applications on Ethereum presents technical challenges, it is feasible with the right expertise and resources. Collaboration between developers from both ecosystems could also accelerate progress and lead to more innovative solutions for cross-chain interoperability.