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 Depends on what u want to secure, so may u create an own private threat model based on questions like : where u live, how many btc u have ?, etc. 
Then i think u have an idea if u need an multisig approach or not 
if its so u may also have a look at mpc solutions like x1 cyperrock. An mpc solution  is different it doesnt use several private keys it splits up an entire private key in parts and some solutions  

Blog.thirdweb.com\mpc