I've definitely experienced this in many areas.  I used to be very into sports.  Now I couldn't care less about sports.  It seems so trivial and unimportant.  My poor husband thought he was marrying a sports fan and now I don't care even a tiny bit.

There are just so many things that no longer seem important.  My priorities have changed since marrying, running a business, having kids, and most of all getting closer to God.