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 yeah, but no. Nostr is horizontal and decentralized from day zero, simplex is a platform well documented unless people start doing third party implementations of clients and server.
I think projects that start like simplex dont end decentralized and open. Would be happy to be wrong! 
 Yep. Even keychat on Nostr is likely to get centralized over time. 

You either incentivize multiple clients, multiple servers, which goes against the duty to maximize revenue of a company, or you end up centralizing everything. 
 There are a lot of servers outside the pool the run. I run two of my own