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 I'm putting all my eggs in the "OPEN source vertically-integrated stack" basket, personally.

We've only see closed source vertical integration/interoperability so far (Apple, etc.) but I believe in (and am building) a future that sees the same UX and power that vertical integration offers, but without the walled gardens. 
 I believe open interoperability will eventually win. Look at Linux. It's the #1 operating system in the world. We can follow a similar path with Nostr and Bitcoin.