Take a look Dr Nutt study, check for psychoactive substances chart by harm potential. You will notice that psylocibin mushrooms or LSD are less toxic than even coffee. In fact you can't even get addicted, as they just don't work being used more often than twice a month. Psilocybin is also the best world treatment for med-resistant depression and I could say thousands more positive things about that... and you know what? when US govt forbid using of them over half a century ago, they lied it makes holes in your brain, shrink your DNA and other bullshit. They also told people that ivermectin is cardiotoxic, while it was great treatment for C19 and moreover its creators received FUCKING NOBLE PRIZE FOR IT BEING ONE OF THE MOST SAFE MEDICINE EVER. I have othet hundreds of reasons to not believe what you quoted... but anyway, dopamine detox? There are thousands better ways to do that. Ibogaine is not even half as good as them. But sincerely, I don't know shit about you, if I were to advise you, I could only harm you. Provide me more info, I'll try my best, but keep in mind that I might be a liar and purposely try to worsen your problems. Never ever believe anyone online when it comes to your mental health.