i guess as part of the onboarding process you could have a user select topics that they definitely aren't interested in and don't want to see those topics.
https://i.imgflip.com/98kge8.jpg
As long as it's really easy to turn it off. I say temporary because it only matters when the amount of topics are small. If you mute bitcoin, GMs, and nostr dev chat, this place is pretty quiet and people may also want to leave.