No. The encryption is not backwards compatible so each other client will have to decide to support it or not.  

 And this replaces the giftwraps which were previously implemented in Amethyst Incognito DMs?  

 Ah, giftwraps is NIP24, and that's still there in the latest Amethyst. 

So, what's the new thing for DMs?  

 Nip44 is used by GiftWraps, which is used by nip 24. :) 

 Of course, that makes sense! 
Nipception 

 :)