Sialoglycan binding triggers spike opening in a human coronavirus

Nature, Published online: 04 October 2023; doi:10.1038/s41586-023-06599-zBinding of a sialoglycan-based primary receptor by the spike protein of the common cold human coronavirus HKU1 triggers conformational changes to a state that would allow binding to a second receptor required for cell entry. #press

https://www.nature.com/articles/s41586-023-06599-z?utm_source=press.coop