It's arguably very hard. How would someone not an expert on Nostr understand where to publish their notes to to be discovered by their intended followership vs where to Read from, and where to Search for etc.

If you want to make sure you are not missing sth/are bing missed then the rational safe option is simply to blsst to as many big relays as possible, and read from as many as possible. It's just the network effect.

I don't see any careful relay curation strategy can live up to that (beside it being totally impractical as there are many less than 50 ppl worldwide who have the knowledge and skills to actually make it work)