I personally like Tailwind best.
It‘s rich but relatively easy to use, because it‘s utility class namings are pretty close to normal CSS.
It‘s super fast to build anything with.
With Bootstrap I had a few issues in the past, hacking on the theme to fit CI needs. In my experience it‘s more complicated and slower, than building from scratch.
Note to say, I‘m a backend developer and only work on this kind of stuff once in a while and I wouldn‘t consider my opinion correct, but very subjective. 

 Thanks nostr:nprofile1qythwumn8ghj7un9d3shjtnwdaehgu3wvfskuep0qy2hwumn8ghj7un9d3shjtnyv9kh2uewd9hj7qgwwaehxw309ahx7uewd3hkctcqyzelp2pgs5mjdrsrcgdfdynmupyt438hq0w9s0m5lge3pu2xsxm7j53wmzz  . It required a build step to purge unused classes right? 

 It only builds the stuff you use