That's quite interesting, I'll be following along! If you make it OSS I'd love to contribute. I have prosumer PCB design, LoRa, and FSK firmware and driver code experience :) I spent a ton of time on power management for AVR's and the radios too. We had pretty strict constraints and LoRa radios can pull a ton of power. e-ink will be interesting, simple i suppose. How big is the lipo?
12mm x 60mm x 110mm. Claimed 10 Ah, but I'll be happy with half. Overkill, probable mistake, and dominates the form factor decisions, but I do miss my Nokia 3210's battery life :p