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 nostr:npub1skvad2l2wrxgdmt6yxk9kt2rjhw5tucjzhf54pktfq2gg0qhgwyqdlaky3 Claude Bernard was very pioneering. Georges Canguilhem has a great text centrally featuring Bernard which is called "Experimentation in animal biology" (can be found in the book of collected Canguilhem texts 'Knowledge of Life'). Absolutely worth adding to your certainly already very long reading list! 🙂