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 Minimise stress and sleep loss by the following:

1. Take off mid morning. Thus you get a good nights sleep the night before you leave and ample time to get to the airport and deal with checkin hassles.
2. Spend the night before the flight at a nice, quiet airport hotel. No last minute stressful ‘getting to the airport’ hassles.

Assuming a 12 hr flight, you will be arriving in late evening according to your body clock. Tired, but not sleep deprived.

You will may need to deal with jet lag (depending on your routing), but you won’t be exhausted, and that’s half the battle.