**Why S-linked glycosylation cannot adequately mimic the role of natural O-glycosylation**

Protein glycosylation is one of the most important post-translational modifications that can be exploited to improve various aspects of therapeutic proteins and industrial enzymes. Different types of glycosylation have a variety of effects on protein properties and functions, and a better understanding of the underlying mechanisms can provide valuable guidance for rational glycoengineering of proteins.

https://phys.org/news/2023-09-s-linked-glycosylation-adequately-mimic-role.html