I wouldn't personally, let it be just your bitcoin wallet... or get a 2nd one to do other non Bitcoin stuff on it, but you do you.

If you want to go deep into the rabbit hole you can fork their code here and make whatever you want
https://github.com/Blockstream/Jade

buy the parts and then build your own case:
https://github.com/Blockstream/Jade/tree/master/diy

or flash it to a jade device...

if you want more 2FA type stuff I would say buy yourself a new yubikey during black friday (the latest ones, cause the old ones have a newly discovered exploit) and use that.

Java cards are hot right now, check out satochip if interested in that space

enjoy the journey