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 Create unlimited ETH create unlimited dollars; you got half the equation solved.  Once that spread ceases to exist there will be no way for intermediaries to facilitate transactions in BTC.  ETH-BTC spread is a proxy for coins available for purchase. 
 I’m confused by your application of the word spread. Typically that term is used for the bid ask delta. ETHBTC being 0.03275btc today is more commonly a ratio or exchange rate.

I also don’t find value talking about when all ETHBTC market pairs shut down and do zero volume. Again that likely won’t happen in the next 20 yrs. 
 Sorry I can see how you find that confusing.  Market makers "spread" their trading.  If you buy bitcoin a market maker sells it to you,  that market maker is now short bitcoin.  To offset his position he goes and buys ETH (or other shitcoin).  That makes him -1BTC +1ETH.  To close out that position that market maker goes and sells the ETH-BTC spread.  Selling that spread (-1ETH +1BTC) offsets the original -1BTC +1ETH spread.  This makes him flat and he nets his dollars profit 
 This helps, thanks 
 Like the ETH-BTC spread is an actual tradable product on most exchanges.  You can buy or sell it, it's a synthetic market.  Maybe not retail but if you watch it on coinbase you will see the market makers doing their thing arbitraging.