nostr:npub1ysemehc2adrdz27k5crmfhcqkmjpjdkqc4pe887ks9s60zfrj40qg8jaay nostr:npub15axslcpkj56yfdtzs4pp5zhtd3ecv3uavpfchsched0r4x0cjl2qwplqq5 

You can also start Firefox with a specific Profile.
Firefox.exe -P "Profilename"
or
Firefox.exe -new-instance -P "Profilename" 
to get a new instance. 

Create a shortcut on your Desktop and you are good to go. 

You could also hack the registry and extend the std apps with the command line options. 

HKEY_LOCAL_MACHINE\SOFTWARE\Classes\htmlfile\shell\open\command

HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\Explorer\FileExts\.html