It’s going to largely depend on your device OS (ie Apple vs Google vs Windows)

I’m iOS so I use Damus primarily and Primal as a secondary client for misc tasks such as looking up npub or note id I want to reference in a post I’m composing on Damus

On computer (web) I use Iris or Primal (but 95% of my #nostr use is on a mobile device)

For Google most people love Amethyst.

I tried YakiHonne for iOS and web and there are features I’m excited about BUT the UI has issues leading to major UX disappointments