if you `e` tag along with the `a` this problem goes away, even if you original event goes away, you have prove that you didn't react in it's current form
you could currently tweet something like "this is cool www.example.com" and then the people on example.com put a swastika
I think there are problems with NIP-33s in general, but I don't think this is one of them
furthermore, when you e-tag a NIP-33 you could publish the NIP-33 you're tagging to your own relay and then prove that the pubkey that published it was maliciously altering content
I think changing a NIP-33 maliciously like this is much more a cryptographically-sound self-own rather than a problem for people tagging it.
crypotgraphically sound self-owns are the worst kind of self-owns
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