Yes there is quite a bit. If you are going to research this just start with 'science behind solfeggio frequencies'. From there I would start at the 1970s and work your way up to now. 
Be aware that its going to go off in many directions. There have been multiple doctors scientists and physicists that have done these experiments all from their individual fields. On top of that they are usually just working with one of the frequencies. 
So what you will encounter is things like 
How frequency A affects cell walls by Dr 1
How frequency B affects DNA by Dr 2
How frequency C affects blood pressure in lab rats by Dr 3
LOL get the idea. So best to pick the field of science you enjoy the most and go down that road. 
But it is fascinating if you are willing to put in the work