Still need to be mindful of having just one large one. Reason is when you spend the size of your stack will be revealed. Spending a whole coin utxo today to buy a T-shirt for 50 bucks creates a change ouput of 27,000 dollars worth of sats for example. Me personally I  think it’s good to have a few smaller ones depending on your spending habits of course. It’s very subjective and I realize everyone’s situation will be different.