In a properly free and voluntarily partitioned society and market, when individuals are succeeding its because they are providing goods and services that others desire and voluntarily trade for.
It's only if you're forced to "deal with the consequences" of others' behavior that don't align with the norm of adding value to society where you run into problems. It should be possible to isolate the drug users and drug dealers in Portland away from one's society, market, community. Those who choose to associate with that scene (either because they desire what it offers, or because they wish to attempt to help heal it at their own expense) will expose themselves to the consequences - "good" and "bad".
Those who wish to be isolated from the consequences should be free to do so.
You assume our fates must all be entangled together. That premise results in unsolvable problems; agreed.
I reject the premise. Because I prefer social norms that reduce conflict and tend to produce solveable problems.